منابع مشابه
Dev113340 1470..1479
The Drosophila transcriptional co-activator protein Yorkie and its vertebrate orthologs YAP and TAZ are potent oncogenes, whose activity is normally kept in check by the upstream Hippo kinase module. Upon its translocation into the nucleus, Yorkie forms complexes with several tissue-specific DNA-binding partners, which help to define the tissue-specific target genes of Yorkie. In the progenitor...
متن کاملDmd052183 1470..1479
4-(3-(Benzyloxy)phenyl)-2-(ethylsulfinyl)-6-(trifluoromethyl)pyrimidine (BETP) represents a novel small-molecule activator of the glucagonlike peptide-1 receptor (GLP-1R), and exhibits glucose-dependent insulin secretion in rats following i.v. (but not oral) administration. To explore the quantitative pharmacology associated with GLP-1R agonism in preclinical species, the in vivo pharmacokineti...
متن کاملLa actividad científica valenciana de la ilustración
sentimentalist pietism that looked to such contemporary continental mystics as Antoinette Bourginon and Madame Guyon. At first sight a heap of contradictions, as Anita Guerrini concludes, Cheyne "was a man of the Enlightenment" not the Enlightenment of "relentless secularisation" but rather that of "sensibility and sociability". In recent years, Cheyne's self-embodied concern with what Guerrini...
متن کاملDmd064386 1590..1600
Herba Epimdii is a traditional Chinese medicine used to treat osteoporosis. Its main pharmacological ingredients are flavonoids. In previous studies conducted in healthy animals, we showed that epimedium flavonoids could be hydrolyzed into secondary glycosides or aglycon by intestinal flora or enzymes, thereby enhancing their absorption and antiosteoporosis activity. To study the medicine in th...
متن کاملFable, c. 1600
The painting. El Greco's Fable is an enigmatic work of art whose meaning and date of origin have provoked much speculation among art historians. In the center of the painting, a young boy (or perhaps a girl?) is blowing at a fire held with the left hand, trying to revive the flame to light a small candle held in the right hand. To the left, behind the youth, a chained monkey with an intelligent...
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ژورنال
عنوان ژورنال: Les Cahiers de Framespa
سال: 2010
ISSN: 1760-4761
DOI: 10.4000/framespa.411